immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
People who are unvaccinated, young children, pregnant women and people with weak immune systems are at the highest risk, officials said. Jeff Capellini, CBS News, 28 Dec. 2025 Apple cider contains antioxidants that people claim can support your immune system, but the alcohol may have the opposite effect. Kathleen Ferraro, Verywell Health, 28 Dec. 2025 May Manage Rheumatoid Arthritis Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that causes the immune system to mistakenly attack healthy cells. Cynthia Sass, Health, 23 Dec. 2025 Even mild soreness after a flu shot is a sign that your immune system is responding — an indication that your body is building protection. Scott Lafee, San Diego Union-Tribune, 23 Dec. 2025 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

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Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 1 Jan. 2026.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

More from Merriam-Webster on immune system

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